San Andreas had the most replay value for me. But as far as the story/missions go, I liked 3 and Vice City a lot. Really liked 4 as well.
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Sig Credit: M.C
Miesha Tate - Urijah Faber - Dustin Poirier - Frankie Edgar - Claudia Gadelha - Tecia Torres - Demian Maia - Jessica Eye - Diaz Bro's