They are Nitric Oxides and yes it is different. Nitric oxide enlarges blood vessels and gives you more "pump" theoretically your muscles get more oxygen, water, fuel this way. They contain Ceatine-Ethyl-Esther (fuel for muscles.) So basically it gets more of what u need to your muscles faster.
But CEE has also never been proven to actually provide the benefits associated withit. If you are new to supplements I would say just start out with a Pure Monohyrdate, or you could buy a Creatine Supp that has both Mono and CEE in it, such as SizeOn by Gaspari Nutrition.