Anderson is one of a kind in his fight game, so far. But size does matter at some point, so I would imagine somehow or another, Brock would lay hands on Silva and pretty much control what happened after that. On the ground, Brock would just have to avoid being submitted long enough to pound out Silva.
But since Silva hasn't fought the best 205ers yet, let's wait and see how he does against the LHW champ and top contenders before asking him to fight the HW champ. He'd at least need some warm-ups in the HW class before a title shot.