Match-up wise, I think he can be a problem for Silva. But there's still some unanswered questions. Can he go 5 rds? How good of a punch (punches) can he take? How well does he adjust if things go wrong? If Weidman had proven that he's excelled in those catagories, then I think Silvas got a real problem on his hands. But since we're dealing with someone who only has 9 career fights, who hasn't proven how exactly well rounded his skill set truly is, who's getting ready to fight someone whos in a league all on his own after he's had a long layoff, then I'd say Silva's a safe bet for the victory.
I do, however, think Weidman has tons of potental, and may very well be the MW champion after Silva retires.